A new, extensive study published in the prestigious Journal of the American Medical Association (JAMA) proves just that: moderate caffeine intake from coffee is associated with a reduced risk of dementia and better cognitive function throughout life.
This study included more than 130,000 participants from the Nurses’ Health Study and Health Professionals Follow-Up studies, who were followed and assessed for up to 43 years, with periodic evaluations of diet and cognitive performance. Over that period, 11,000 cases of dementia were recorded, enabling researchers to track how coffee-drinking habits affect the brain over several decades.
Moderation leads to significant results
Participants who regularly consumed two to three cups of coffee a day (up to 300 mg of caffeine) had a significantly lower risk of developing dementia, by as much as 18 percent, compared with those who consumed no caffeine or only lower doses.
In addition, those who drank more coffee reported fewer memory-related challenges and scored better on objective tests of mental function. In people who consumed around two to three cups a day, brain function declined more slowly. This roughly corresponds to about half a year’s difference in its more pronounced aging compared with “non-drinkers.”
What science says about the benefits of caffeine
These links are no coincidence: caffeine affects several biological pathways that are crucial for brain health, from regulating amyloid and tau proteins, to reducing neuroinflammation, and improving vascular function and insulin sensitivity. These processes are closely associated with a lower risk of neurodegenerative diseases such as Alzheimer’s.
Still, it is important to remember not to overdo it, because the greatest benefits were observed with moderate caffeine intake, up to three cups of coffee a day; the effect does not increase significantly among those who drink extremely large amounts.
This intake should not be seen as a “cure,” but it can be an important support for a healthier lifestyle that benefits the brain. When you enjoy your favorite drink and ritual, remember that it can also be a small but long-term investment in your cognitive health.